Saturday, April 20, 2024

Applying Innovative Methods of Nanotechnology: High-Performance Solution to Treat Rare Diseases

 To start with, rare diseases or orphan diseases that affect around 8% of the population, which is more than 400 million people, generally have a genetic origin and it’s pretty difficult to diagnose them in the initial stages. Living with rare diseases requires a long and challenging treatment process requiring specific control and ongoing management. Applying advanced treatment enables the development of new approaches to diagnose, track, and provide specific medicines. The fact is there’s no suitable treatment for 90% of cases of orphan diseases, so nanotechnology will offer healthcare specialists effective therapies and advanced diagnosing to improve the patient’s health condition. 

  What’s the principle of nanomedicine? To be short, its mission is to craft a particular nanomaterial that can be nanoparticles or nanocarriers, and molecules to create a biocompatible carrier to deliver medicines to the defined cells. These nanoparticles are designed to attract diseased cells and treat them properly. Such an approach allows for the mitigation of the damage to healthy cells and detects the disease at its early stages.

  For example, dealing with hemophilia, an inherited bleeding disorder, when even a little trauma can cause uncontrolled bleeding. Moreover, this disease can lead to brain development issues, intracranial bleeding, and joint damage. If you are dealing with muscles Pain the zerodol sp tablet is the Best choice, So, today due to close cooperation and partnership of all-level medical specialists and biotechnology engineers, it became real to apply proper nanomedicines. Hence, with the development of nanotechnology and its implementation in medicine, artificial blood or its substitutes can be used to treat any blood disorder disease, i.e. gas carrier components for erythrocytes, immune response components for white blood cells, and hemostasis-responsive components for platelets.

  Unfortunately, less than 5% of rare diseases have one proven treatment plan called orphan therapy. The reason is a lack of proper knowledge base, regulatory issues, risks with drug production, and absence of effective practices implementation. That’s why it’s crucial to find new treatments.

  What’s more, orphan diseases are predominantly progressive and life-threatening, and 70% of them are detected in children. The more dramatic fact is that we face leakage of medical research and high-quality expertise about rare diseases. So, nanotechnology-related treatment for rare diseases is a must for the present medical field.

  Considering the fact that nanomedicine was designed for cancer treatment, the researches show that nano methods can be applied to treat and prevent atherosclerosis. This chronic disease causes various cardiovascular diseases that are the main cause of lethal outcomes. So, what does atherosclerosis treatment involve? Scientists from South Korea from KAIST produced cargo-switching nanoparticles that are a combination of two wide-spread drugs for atherosclerosis treatment called cyclodextrin and statin. Cargo-switching nanoparticles are effective in reducing cholesterin cells and macrophages in the vessels that are centers of atherosclerosis plaques and inflammation.

  That means thanks to the cutting-edge nanotechnologies, it’s absolutely useful to apply non-invasive delivery of nanomedicines in treating atherosclerosis instead of bypass surgery, atherectomy, and endarterectomy for removing blood clots and fatty deposits from arteries. All in all, nanomedicine is a highly innovative and effective solution to treat any chronic diseases, including rare ones, and avoid intense side effects. Using nanotechnologies and non-invasive ways enables them to target of abnormal cells and organs, increase the efficiency of the used drugs, and get painless therapy for patients.

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